What’s New in SyMAP
Release notes for the SyMAP platform: what shipped, where to find it, and why it matters.
SyMAP 2.0
August 2026
Our biggest release yet, and the one that joins the platform up. International reference pricing and US MFN policy now run as a single simulation rather than one feeding the other by hand. The voluntary agreements get a deal designer of their own. And Optimizer Studio searches the strategy space for you, with an assistant that can propose the changes and, once you approve them, make them.
The headlines
Reference Pricing, MFN and Revenue in One Simulation
Reference pricing and MFN used to be two separate exercises: build the IRP model, save the results, then load them into the MFN model as inputs. They are now one run. Change a price in Germany and the reference cascade, the US benchmarks it feeds, the rebates and the revenue all move together.
- International reference pricing and all four US MFN pathways in one simulation, on one portfolio and one set of prices
- Multi-year revenue across US channels and international markets, built from the simulated prices rather than typed in from somewhere else
- Every run can write its own first-draft analysis: the drivers, the risks, and what changed since last time
Voluntary Agreements and the MFN Deal Designer
A fourth MFN pathway, and a place to design the deal itself. Set the terms you are contemplating, see what they do to your US revenue, and put them straight up against GENEROUS, GLOBE and GUARD before you sign anything.
- Design an agreement the way it is actually structured: start date, participation timing, and which channels are in scope
- Existing drugs follow the Medicaid route and new launches the prospective route, assigned automatically, with per-drug overrides where you need them
- Compare a designed deal against the CMS models and against no policy at all, and layer Section 232 tariff assumptions over any of it so the tariff trade-off sits in the same picture as the pricing one
Optimizer Studio, and AI That Can Act On It
Testing scenarios one at a time only takes you so far. Give Optimizer Studio a goal and the levers you are willing to pull, and it searches the combinations, then shows exactly why the winner wins. The assistant can now put forward optimisations of its own, and carry them out once you have approved them.
- Set an objective (revenue, exposure, or a threshold) and choose your levers: launch timing and sequence, the price in each market, and your US pricing choices
- A driver waterfall breaks the winning strategy down factor by factor, so the recommendation is explainable rather than a black box
- The assistant proposes an optimisation and applies it only where an administrator has allowed that action and a person has confirmed it, with every proposal and decision recorded
Also in 2.0
Every feature in depth: Global Pricing · SyMAP MFN · SyMAP IRP. The story behind this release is in Introducing SyMAP 2.0, the MFN release in Introducing SyMAP MFN, and the original IRP launch in Introducing SyMAP IRP.