SyMAP 2.0 · Continually advancing

From pricing simulation
to global strategy.

SyMAP 2.0 connects the questions that shape a product’s commercial future: international prices, US policy exposure, patient demand, global revenue and the alternatives worth exploring.

One product dataset.
More connected decisions.

Build a reusable foundation in Data Hub. Model the scenario. Inspect the result. Keep developing the product outlook as the evidence and the landscape change.

Updated monthlyOngoing development across modelling, forecasting and optimisation.

One dataset. A connected forecast.

Bring the whole product
into the picture.

The integrated forecast brings together international price evolution, US policy effects and monthly demand. Patient models connect population and treatment assumptions to the volume forecast that underpins revenue.

Reusable foundations

Start in Data Hub.

Store product and market inputs, use shared libraries for rules, patient models and FX, and keep saved runs available to review and compare.

Explore Data Hub

From patients to revenue

See what drives demand.

Model eligible populations, competitive uptake and persistence by indication. Connect the resulting product demand with price paths, rebates and launch timing.

Explore patient & revenue forecasting

A dataset that develops with the product

  1. Early planningBuild the initial assumptions
  2. LaunchRefine prices, timing and demand
  3. LifecycleExplore indications and evolving markets
Follow the product lifecycle

Optimizer Studio

Explore the complete plan.
Understand the trade-offs.

Pricing and launch studies evaluate alternatives against your chosen objective. Launch-sequence search brings the selected IRP, MFN and revenue effects together, moving from broader timing choices towards finer launch dates.

  1. Search the choices

    Explore price ranges, launch timing, corridors, targets and combinations of commercial levers.

  2. Inspect the contribution

    Compare your original plan with the best evaluated alternative and examine the drivers of the revenue difference.

  3. Revisit the strategy

    Replay an earlier strategy against updated assumptions to see whether the result still supports the decision.

Explore pricing & launch optimisation
SyMAP / Optimizer Studio
SyMAP Symara demo launch plan and net revenue summary comparing the current plan with the best evaluated alternativeInspect the result
Actual product view with illustrative data.

Deeper analysis across connected capabilities

Make the assumptions explicit.
Make the alternatives comparable.

US MFN modelling

Compare policy and agreement choices.

Configure voluntary-agreement timing, product pathways and channel scope. Compare with baseline and CMS-model scenarios, with tariff assumptions where relevant to the study.

Explore US MFN modelling

International reference pricing

Inspect the rules and thresholds.

Custom formulas, comparison views and sensitivity analysis support closer examination of the baskets, timing and price changes that shape international outcomes.

Explore international reference pricing

GLOBE final rule modelling

SyMAP now incorporates the GLOBE final rule’s timing, international benchmarks and additional Part B rebate calculations.

  • Choose which drugs to assess and set their entry, exit and coverage assumptions.
  • Inspect Method I and quarterly Method II benchmarks, including GDP purchasing-power adjustments.
  • Review additional rebates above the Part B inflation rebate and their effect on forecast revenue.
  • Test a hypothetical extension beyond the initial period, with your own duration and coverage assumptions.

Compare pricing and launch plans, assess exposure after GENEROUS or model a permitted withdrawal using the relevant agreement terms. When updating an existing forecast, review its saved entry and exit settings before running it again.

Watch the GLOBE walkthrough

Built around your team’s work

From the first import
to the next review.

Keep the modelling workflow connected to the way your team prepares data, shares assumptions and explains decisions.

  1. Bring data into the workflow

    Import supported spreadsheets, or connect existing models to SyMAP simulations through the API. Reuse saved datasets across compatible tools.

  2. Share the foundation

    Shared datasets and libraries, role-based access, multi-factor sign-in and organisation branding support a consistent team workspace.

  3. Keep the reasoning visible

    Saved runs, comparison and AI-assisted analysis help explain results. Governed AI actions require confirmation and retain an audit trail.

Monthly product development extends the capabilities your team uses to respond to changing pricing and market-access questions.

Explore the integrated platform

The product story

How the platform developed.

SyMAP 2.0 launched in August 2026. The capabilities above reflect its continuing development.

Explore the original announcements
  1. SyMAP 2.0: the integrated platform
  2. US MFN modelling joins the workflow
  3. The international reference pricing foundation

Your next decision

See what SyMAP 2.0
could change for your team.

Explore the current platform in a demo built around your products, markets and decisions.