From the patient to the commercial outcome

What is driving demand?
What does it mean for revenue?

Connect epidemiology and treatment assumptions to monthly product demand. Bring that demand into the same forecast as international prices and US policy effects.

Build the demand forecast

  1. 01
    Population & epidemiology

    Incidence or prevalence

  2. 02
    Diagnosis & eligibility

    Define the treated population

  3. 03
    Uptake & persistence

    Product and competitor assumptions

  4. 04
    Monthly product demand

    Packs or treatment-years

One connected outlook

Patients.
Prices.
Global revenue.

See how demand and changing net prices shape the result over time.

By marketBy monthAcross the product
Connect the price pathInternational reference pricingUS MFN scenariosLaunch & access assumptions

Inside SyMAP

Model the patients.
See the commercial impact.

Follow the patient journey, connect demand to your product and explore the revenue outlook.

SyMAP / Patient JourneyActual product view
SyMAP DMD demo patient model covering seven countries, with France selected and a patient journey showing population, eligibility, peak monthly starts and patients on therapyInspect the workspace

See how the patient population becomes product demand.

Follow the model from population and eligibility through treatment uptake, patients on therapy and consumption, using market-specific assumptions. The France view includes calculated peak patient starts and patients on therapy from the illustrative DMD model.

SyMAP / Patient ForecastActual product view
SyMAP DMD demo patients on therapy over time in France, Germany, the United Kingdom, Japan, Italy and the United States, with a July 2034 tooltipInspect the workspace

See how patient demand develops across markets.

Follow patients on therapy across six markets in the DMD demo. The monthly curves bring launch timing, uptake and treatment persistence into view; the July 2034 tooltip lets you inspect each market at the same point in time.

SyMAP / Connected Patient ModelActual product view
SyMAP integrated forecasting setup with the Symara FGFR2-positive CCA patient model attached and the Symara product selected to receive its demandInspect the workspace

Connect the patient model to the product forecast.

Attach an indication-specific patient model and select the product that receives its demand. This Symara demo links the patient model to its pricing dataset; additional models can represent distinct patient populations within the same forecast.

SyMAP / Patient-Driven RevenueActual product view
SyMAP annual net revenue from the connected Symara patient model and annual-treatment pricing dataset, with a 2035 regional tooltip and the selected CMS Models policy scenarioInspect the workspace

Turn patient demand into the commercial outlook.

This Symara demo combines patient demand with annual-treatment prices, international reference pricing and the selected US MFN scenario. Review net revenue by region over time, then inspect the contributions to the 2035 total.

Actual SyMAP workspaces. Illustrative product data. Select an image to inspect the detail.

Multi-indication forecasting

Different indications.
One product timeline.

An indication expansion changes the product outlook. Model each distinct patient population with its own patient flow, launch date and uptake assumptions, then combine demand for the product.

Keep each indication distinct

Model the population and treatment dynamics that make each opportunity different.

See the combined contribution

Bring monthly patient demand together to explore the effect of indication timing and uptake on the forecast.

Separate assumptions. Connected demand.

A
Indication A

Patient flow · Launch · Uptake

B
Indication B

Patient flow · Launch · Uptake

Combined monthly demand

Attached to the product forecast

Make the forecast explainable

Follow the change.
Understand the consequence.

Review patient demand, price evolution and revenue together. Move from the global result to the markets and assumptions behind it.

What if uptake is slower?

Compare uptake assumptions to see how patients on therapy, monthly demand and net revenue develop against your base case.

What if an indication launches later?

Shift an indication’s launch timing and compare its demand contribution and the effect on total product net revenue.

What if prices or US MFN change?

Keep demand assumptions consistent while comparing international price paths and selected US MFN scenarios. See which markets drive the net revenue difference.

The same product, throughout its lifecycle

Build on what you know.
Refine what comes next.

Start with the product dataset in Data Hub. Attach patient models and choose your pricing and policy assumptions. Refine those inputs as your product and the evidence evolve.

One product dataset

Products, packs, markets and pricing

  1. 01Early planning

    Explore patient potential and pricing assumptions.

  2. 02Launch

    Refine timing, access and market uptake.

  3. 03Lifecycle

    Revisit indications, competition and price evolution.

Questions, answered

A clearer starting point.

Can we use our existing volume forecast?

Yes. Keep your dataset volume forecasts, or attach patient models to selected products. Products without an attached model retain their dataset volumes, so you can add patient modelling where it is most useful.

Do we need detailed patient data for every market?

No. Model priority markets in detail and extend the outlook to other markets using reference-market scaling, launch timing and access assumptions. Refine the country models as better evidence becomes available.

How do patients become product volumes?

For pack-priced products, dosing and pack details convert patient demand into packs. For annual-treatment products with chronic persistence, patients on therapy become treatment-years. The integrated forecast applies the product’s prices to those volumes.

Can different indications have different launch dates?

Yes. Each distinct patient population can have its own model, launch timing and uptake profile. Their monthly demand is then combined for the product.

Does patient forecasting connect to MFN?

An attached patient model can supply demand inputs to eligible MFN calculations as well as revenue. The relevant calculation depends on the policy scenario and settings you select. Explore US MFN modelling in SyMAP.

Your next decision

Bring your forecast.
Explore its drivers.

Explore your patient assumptions, product demand and pricing scenarios in a demo tailored to your forecasting questions.