Three new modules in SyMAP 2.0: forecasting, patients, optimisation →

SyMAP Global Pricing: Pharma Pricing Strategy & Revenue Forecasting Software

Join US and ex-US pharmaceutical pricing end-to-end: forecast revenue under every policy path, model patient flow, and let the optimiser find the strategy that wins.

Pricing is now a single global challenge

A discounted launch in one country can cascade through IRP networks and reappear in US MFN benchmarks. SyMAP Global Pricing integrates domestic and international pharmaceutical pricing analysis into one strategic framework: connecting US channel exposure, ex-US list and net prices, IRP pathways, and MFN benchmarks. In SyMAP 2.0 it grows three major new modules: a Revenue Forecasting workspace with AI-written run analysis, patient-based forecasting, and Optimizer Studio, an optimisation engine over the whole pricing model. Read the thinking behind the integrated approach in The End of Two Silos.

International Price Strategy
  • Model how ex-US pricing decisions flow through to MFN benchmarks
  • Tune ex-US prices to manage the US MFN benchmark
  • Map which markets reference which, and how they interact
Global Price Corridors
  • Define and maintain acceptable pricing ranges across markets
  • Model how policy changes compress or expand your corridor
  • Flag decisions that breach your agreed price corridor
One Data Model, End to End
  • US channel exposure, ex-US prices, IRP pathways, and MFN benchmarks in one scenario
  • Enter a price once: every module reads the same dataset
  • Unified runs keep pricing, forecasting, and comparison views consistent

Revenue Forecasting New in 2.0

A dedicated forecasting workspace that joins the pricing engines to multi-year revenue projection: US payer channels and ex-US markets in one view, attributed under the policy path you choose.

Integrated Projections
Revenue built directly from simulated prices: IRP outcomes, MFN rebates, and channel mix flow straight into the forecast. No copy-paste between models.
Policy-Path Attribution
Forecast under voluntary-agreement, CMS-model, or baseline policy scenarios, with per-channel revenue attribution showing exactly where the exposure sits.
AI Run Analysis
Every forecast run can generate a structured, AI-written analysis: the drivers, the risks, and how this scenario differs from the last one. Your analyst’s first draft, on every run.
SyMAP: multi-year revenue projection charts across channels
SyMAP: price evolution feeding revenue forecasts
SyMAP: Revenue Forecasting workspace with AI Analysis panel
SyMAP: patient forecasting curve editor with uptake and persistence curves
SyMAP Optimizer Studio: driver waterfall attribution for the winning strategy

Patient Forecasting New in 2.0

Ground your revenue in epidemiology, not just price. Build patient flow models and drive volume from the population up.

Patient Flow Models
Model incidence, prevalence, diagnosis, and treatment flow as a connected graph, validated as you build it.
Curve Library
Adjustable uptake, erosion, and persistence curves: pick an archetype, calibrate it to your market, and see the shape respond live.
Built-In Model Library
Start from archetype presets or calibrated demonstration models (including rare-disease and Parkinson’s examples), then attach models to products, including multi-indication portfolios.

Optimizer Studio New in 2.0

Don’t just test scenarios: search the strategy space. Optimizer Studio runs optimisation studies over the full pricing model, and shows its working.

Optimisation Studies
Set an objective (revenue, exposure, or a threshold) and choose your levers: launch timing and sequence, ex-US prices, US pricing levers. The study explores the combinations trial by trial.
Waterfall Attribution
See why the winning strategy wins: a driver waterfall decomposes the result factor by factor, so the recommendation is explainable, not a black box.
Replay on Today’s Setup
Markets move. Replay a winning lever set against your updated setup and get an honest then-vs-now comparison before you act on it.

Global Pricing Use Cases

Launch Sequence Strategy
Let Optimizer Studio search launch orders across markets to maximise revenue while managing IRP and MFN exposure, then inspect the waterfall to see why the winner wins.
Cross-Market Impact Analysis
Model how pricing decisions in one market cascade through global reference networks and into US benchmarks.
Lifecycle & Indication Planning
Plan pricing across lifecycle stages and indication launches, with patient-based volume underneath the revenue line.
Policy Scenario Forecasting
Forecast revenue under voluntary, CMS, and baseline policy paths (with tariff overlays where relevant) and brief leadership from the AI run analysis.

SyMAP Global Pricing FAQs

What is SyMAP Global Pricing?
SyMAP Global Pricing integrates domestic and international pricing analysis into a unified strategic framework. It connects IRP pathways with MFN benchmarks from GENEROUS, GLOBE, GUARD, and voluntary agreements, and adds revenue forecasting, patient-based forecasting, and optimisation on top, so pricing decisions and their revenue consequences live in one model.
How does Revenue Forecasting work?
The Revenue Forecasting workspace builds multi-year projections directly from the simulation engines: IRP price evolution, MFN rebates, US channel mix, and ex-US revenue in one view. Forecasts run under a chosen policy scenario (voluntary, CMS, or baseline), and each run can generate an AI-written analysis of its drivers and risks.
What is Patient Forecasting?
Patient Forecasting drives volume from the population up: patient flow models built as visual flow maps, with a ready-made library of uptake, erosion, and persistence curves. Start from built-in archetypes or calibrated demonstration models, then attach a model to a product (including multi-indication portfolios) to underpin revenue with epidemiology.
What is Optimizer Studio?
Optimizer Studio runs optimisation studies over the full pricing model. You set the objective and the levers (launch timing and sequence, ex-US prices, US pricing levers) and the study searches the combinations trial by trial. Results come with a driver waterfall explaining why the winning strategy wins, threshold analysis for tipping points, and replay to re-test a winning lever set against your updated setup.
Do the SyMAP modules share data?
Yes, that’s the point. One product dataset drives IRP simulation, MFN modelling, revenue forecasting, and optimisation alike. Enter an ex-US price once and it flows through reference networks, MFN benchmarks, and the revenue forecast consistently.

See the whole picture

A live walkthrough: one dataset, one scenario, priced, forecast, optimised, and explained.